DETERMINATION OF CLIMATE-BASED DAYLIGHT METRICS UNDER 15 CIE (INTERNATIONAL COMMISSION ON ILLUMINATION) STANDARD SKIES AND THREE REPRESENTATIVE SKIES

Daylighting serves as a crucial sustainable strategy in assessing the built environment.Climate-based daylight metrics (CBDMs) have been widely employed to evaluate the dynamic performance of daylight.However, conventional CBDM calculations heavily rely on time-consuming full-scale computer simulations.In addition, the CBDMs need representative ann

Abstract Background Cell cycle dysregulation is common in human malignancies, and CDK4/6 inhibitors targeting cell cycle have potential antitumor activity.SHR6390 is a novel small molecule inhibitor specifically targeting the CDK4/6 pathway.However, the role of SHR6390 in esophageal squamous cell carcinoma (ESCC) remains unknown, which will be inve